HTuO Biosciences

HTuO Biosciences has one mission: to make the process of designing drugs faster and more efficient, reducing the cost of bringing drugs to market. We believe that the best way to improve our understanding of molecular interactions is to create more accurate models, both of the molecules of interest as well as the solvent in which they're interacting.

Water is the solvent in which nearly all biologically relevant chemical interactions occur. If you can model water accurately, you gain insight into the behaviour of everything in it, including drugs and drug targets, lowering the barrier to effective drug design.

“Out of 66 clinical candidates, published by the Journal of Medicinal Chemistry in the 2016–2017 period, none originated as a virtual screening hit. It is a fact that predicting binding affinities is terribly difficult, and one of the main compounding factors is the solvent’s effect.”

— Defelipe et al., Solvents to Fragments to Drugs: MD Applications in Drug Design, Molecules 2018, 23, 3269

If you'd like to learn more about our company, contact us at info@htuobio.com